Fig. 8From: Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult ratsScutellarin enhanced HES-1 expression in astrocytes after MCAO. HES-1 expression is undetected in astrocytes in the sham (A1–3). Its expression (red) was moderately induced after MCAO in GFAP positive astrocytes (green) at 7 days (B1–3) but was attenuated at 14 days (D1–3). However, HES-1 expression was markedly increased in hypertrophic astrocytes in scutellarin treated MCAO rats at 7 (C1–3) and 14 days (E1–3) in comparison to the matching control groups (B1–3, D1–3). Scale bars: 50 µm. DAPI-blue Back to article page