Fig. 10

Scutellarin enhanced TNF-α expression in astrocytes after MCAO. TNF-α expression (red) was absent in astrocytes in the sham (A1–3). It was induced in GFAP positive astrocytes (green) at 3 and 7 days (B1–3) after MCAO, but the expression subsided at 14 days (D1–3). In MCAO rats treated with scutellarin (C1–3, E1–3). TNF-á expression in astrocytes was markedly enhanced being most pronounced at 7 days when compared with the matching MCAO control groups (B1–3, D1–3). Scale bars: 50 µm. DAPI-blue