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Fig. 6 | BMC Neuroscience

Fig. 6

From: Neuroprotective effects of Cerebrolysin in triple repeat Tau transgenic model of Pick’s disease and fronto-temporal tauopathies

Fig. 6

Effects of CBL treatment in behavioral alterations in 3R Tau transgenic mice. Mice were evaluated for context-dependent learning in an open field area using a Kinder SmartFrame Cage Rack Station activity monitor system. a, b Levels of total activity and rearing in the cage in the 3–6 month group. c Nesting behavior in the cage of the 3–6 month group. d, e Levels of total activity and rearing in the cage in the 6–9 month group. f Nesting behavior in the cage of the 6–9 month group. For analysis, N = 10 non-tg and N = 10 3R Tau tg mice from each age and treatment group. *P < 0.05 when compared to non-tg control using one way ANOVA with Dunnet’s post hoc test. # P < 0.05 when compared to vehicle-treated tg mice control using one way ANOVA with Dunnet’s post hoc test

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BMC Neuroscience

ISSN: 1471-2202

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