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Fig. 3 | BMC Neuroscience

Fig. 3

From: Profilin 1 with the amyotrophic lateral sclerosis associated mutation T109M displays unaltered actin binding and does not affect the actin cytoskeleton

Fig. 3

Unaltered actin cytoskeleton in HEK293 cells overexpressing wildtype and mutant V5-PFN1. HEK293 cells transfected with plasmids coding for wildtype and mutant V5-PFN1 were stained for exogeneous PFN1 (anti-V5) and endogeneous F-actin (Phalloidin). Note the formation of aggregates of the V5-PFN1 C71G protein in roughly 50 % of cells reported previously [2]. Scale bar is 10 µm

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BMC Neuroscience

ISSN: 1471-2202

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