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Fig. 6 | BMC Neuroscience

Fig. 6

From: Higher intrinsic network excitability in ventral compared with the dorsal hippocampus is controlled less effectively by GABAB receptors

Fig. 6

Higher incidence, rate and area of spfps-nmda in VH compared with DH. a Simultaneous recordings of spfps-nmda from the CA1 stratum radiatum of a DH and a VH slice taken from the same animal and bathed in 50 μM PTX and 20 μM CNQX. One minute-long records (traces on the left) and single events (traces on the right) are shown. Note that spfps-nmda was larger and occurred at a higher rate in VH compared with the DH slice. b The incidence, rate and area of spfps-nmda were significantly greater in VH compared with DH slices. Asterisks denote statistical significance between DH and VH values (Mann–Whitney U test test, at *p < 0.05 or **p < 0.005). c Diagram illustrating the relationship between the rate of occurrence of spfps-nmda and the slice position along the dorsoventral axis of the hippocampus. Only slices taken from the VH displayed positive correlation in their rates of spfps-nmda as approached the end of the hippocampus structure (F = 2.5, p < 0.05). Note that slices taken from the most extreme positions did not show spfps-nmda. The medial part of the hippocampus (i.e. locations 9-13) is not shown for clarity

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