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Table 2 Analysis of cell types via marker genes

From: T cell deficiency in spinal cord injury: altered locomotor recovery and whole-genome transcriptional analysis

System

Cell type

Marker

Acute

Chronic

Greater

log2FC

Q

Greater

log2FC

Q

Innate immune system

Dendritic cell

CD83

 

0.14

0.77

 

−0.02

0.98

Macrophage

CD68

 

0.66

0.12

 

0.47

0.07

  M1 macrophage

CD86

 

0.50

0.16

 

−0.18

0.68

  M2 macrophage

CMAF

 

0.46

0.12

 

0.32

0.18

Mast cell

KIT

 

−0.05

0.95

AN

0.57

0.01

Granulocyte

Ly6C

 

0.19

0.91

 

0.26

0.87

NK cell

KLRA1

 

0.63

0.15

AN

1.20

<0.01

Adaptive immune system

T cell

CD3g

SD

−2.37

0.02

 

−0.88

0.17

  Helper T cell

CD4

SD

−1.20

<0.01

 

−0.25

0.36

      Th1 cell

CCR5

 

−0.12

0.83

 

−0.14

0.72

      Th2 cell

CXCR4

AN

0.65

0.02

AN

0.49

0.01

  Cytotoxic T cell

CD8a

AN

1.39

<0.01

 

−0.37

0.16

B cell

CD19

 

−1.29

1.00

 

0.74

1.00

Central nervous system

Neuron

NEFH

 

−3.31

0.05

SD

−1.90

<0.01

Oligodendrocyte

PLP

 

−1.27

0.30

 

−0.21

0.82

Astrocyte

GFAP

 

−1.48

0.34

 

0.00

1.00

  1. FC fold change (AN FKPM divided by SD FKPM); Q, false discovery rate-adjusted P value