|
System
|
Cell type
|
Marker
|
Acute
|
Chronic
|
|---|
|
Greater
|
log2FC
|
Q
|
Greater
|
log2FC
|
Q
|
|---|
|
Innate immune system
|
Dendritic cell
|
CD83
| |
0.14
|
0.77
| |
−0.02
|
0.98
|
|
Macrophage
|
CD68
| |
0.66
|
0.12
| |
0.47
|
0.07
|
|
M1 macrophage
|
CD86
| |
0.50
|
0.16
| |
−0.18
|
0.68
|
|
M2 macrophage
|
CMAF
| |
0.46
|
0.12
| |
0.32
|
0.18
|
|
Mast cell
|
KIT
| |
−0.05
|
0.95
|
AN
|
0.57
|
0.01
|
|
Granulocyte
|
Ly6C
| |
0.19
|
0.91
| |
0.26
|
0.87
|
|
NK cell
|
KLRA1
| |
0.63
|
0.15
|
AN
|
1.20
|
<0.01
|
|
Adaptive immune system
|
T cell
|
CD3g
|
SD
|
−2.37
|
0.02
| |
−0.88
|
0.17
|
|
Helper T cell
|
CD4
|
SD
|
−1.20
|
<0.01
| |
−0.25
|
0.36
|
|
Th1 cell
|
CCR5
| |
−0.12
|
0.83
| |
−0.14
|
0.72
|
|
Th2 cell
|
CXCR4
|
AN
|
0.65
|
0.02
|
AN
|
0.49
|
0.01
|
|
Cytotoxic T cell
|
CD8a
|
AN
|
1.39
|
<0.01
| |
−0.37
|
0.16
|
|
B cell
|
CD19
| |
−1.29
|
1.00
| |
0.74
|
1.00
|
|
Central nervous system
|
Neuron
|
NEFH
| |
−3.31
|
0.05
|
SD
|
−1.90
|
<0.01
|
|
Oligodendrocyte
|
PLP
| |
−1.27
|
0.30
| |
−0.21
|
0.82
|
|
Astrocyte
|
GFAP
| |
−1.48
|
0.34
| |
0.00
|
1.00
|
-
FC fold change (AN FKPM divided by SD FKPM); Q, false discovery rate-adjusted P value
