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Table 2 Analysis of cell types via marker genes

From: T cell deficiency in spinal cord injury: altered locomotor recovery and whole-genome transcriptional analysis

System Cell type Marker Acute Chronic
Greater log2FC Q Greater log2FC Q
Innate immune system Dendritic cell CD83   0.14 0.77   −0.02 0.98
Macrophage CD68   0.66 0.12   0.47 0.07
  M1 macrophage CD86   0.50 0.16   −0.18 0.68
  M2 macrophage CMAF   0.46 0.12   0.32 0.18
Mast cell KIT   −0.05 0.95 AN 0.57 0.01
Granulocyte Ly6C   0.19 0.91   0.26 0.87
NK cell KLRA1   0.63 0.15 AN 1.20 <0.01
Adaptive immune system T cell CD3g SD −2.37 0.02   −0.88 0.17
  Helper T cell CD4 SD −1.20 <0.01   −0.25 0.36
      Th1 cell CCR5   −0.12 0.83   −0.14 0.72
      Th2 cell CXCR4 AN 0.65 0.02 AN 0.49 0.01
  Cytotoxic T cell CD8a AN 1.39 <0.01   −0.37 0.16
B cell CD19   −1.29 1.00   0.74 1.00
Central nervous system Neuron NEFH   −3.31 0.05 SD −1.90 <0.01
Oligodendrocyte PLP   −1.27 0.30   −0.21 0.82
Astrocyte GFAP   −1.48 0.34   0.00 1.00
  1. FC fold change (AN FKPM divided by SD FKPM); Q, false discovery rate-adjusted P value
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BMC Neuroscience

ISSN: 1471-2202

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