TY - JOUR AU - Kanno, Haruo AU - Ozawa, Hiroshi AU - Tateda, Satoshi AU - Yahata, Kenichiro AU - Itoi, Eiji PY - 2015 DA - 2015/10/08 TI - Upregulation of the receptor-interacting protein 3 expression and involvement in neural tissue damage after spinal cord injury in mice JO - BMC Neuroscience SP - 62 VL - 16 IS - 1 AB - Necroptosis is a newly identified type of programmed cell death that differs from apoptosis. Recent studies have demonstrated that necroptosis is involved in multiple pathologies of various human diseases. Receptor-interacting protein 3 (RIP3) is known to be a critical regulator of necroptosis. This study investigated alterations in the RIP3 expression and the involvement in neural tissue damage after spinal cord injury (SCI) in mice. SN - 1471-2202 UR - https://doi.org/10.1186/s12868-015-0204-0 DO - 10.1186/s12868-015-0204-0 ID - Kanno2015 ER -