Fig. 5
From: High-fat diet-induced obesity exacerbates kainic acid-induced hippocampal cell death
Effects of HFD on KA-induced hippocampal Nrf2 and HO-1 expression. a Western blot analysis of Nrf2. b Representative immunofluorescence images of Nrf2 (red) and NeuN (green) in the hippocampus of ND and HFD mice with or without KA treatment. Scale bar 50 µm. c Western blot analysis of HO-1 in the hippocampus of ND and HFD mice with or without KA treatment. Densitometry values for Nrf2 and HO-1 were normalized to β-actin and expressed as fold change relative to the ND group. Data are shown as mean ± SEM (n = 4 mice per group). *p < 0.05 versus ND. # p < 0.05 versus HFD. † p < 0.05 versus ND + KA