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Fig. 4 | BMC Neuroscience

Fig. 4

From: Expression profiling of the ubiquitin conjugating enzyme UbcM2 in murine brain reveals modest age-dependent decreases in specific neurons

Fig. 4

UbcM2 expression is decreased in aged mouse brains. A Representative photomicrographs showing decreased UbcM2 expression in aged (b, d, f, h, j) relative to young control (a, c, e, g, i) brains in the 5 structures with >10 % differences. 20×, size bar 30 μm. B Average expression of UbcM2 in whole brain, consisting of the analysis of 22 substructures, indicating a 5.5 % global decrease in aged brain relative to young control. n = 5 in triplicate; p value = 0.046. C Average UbcM2 expression in the 5 substructures that exhibited a >10 % decrease. Asterisks denote p < 0.05. CB (cerebellum granule cells), MC1 (primary motor cortex), ON (olfactory nucleus), SC (superior colliculus), VC2 (secondary visual cortex)

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BMC Neuroscience

ISSN: 1471-2202

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