Table 2 Changes in relative ripple rates immediately after cognitive stimul ation (computed in 500 ms moving window, significant changes compared to baseline −0.6 s to −0.1 s are highlighted)

Epileptic hippocampus

 Time (s)

Baseline

0–0.5

0.1–0.6

0.2–0.7

0.3–0.8

0.4–0.9

0.5–1.0

0.6–1.1

0.7–1.2

0.9–1.4

1.0–1.5

1.1–1.6

1.3–1.8

 Mean RR

0.7911

0.7595

0.7445

0.7630

0.8172

0.8130

0.7939

0.7842

0.8262

0.8951

0.9374

1.0221

1.1213

 SD

0.2896

0.2174

0.2584

0.2941

0.3187

0.3711

0.3240

0.3025

0.3405

0.3934

0.3821

0.3699

0.3173

 P

1.0000

0.3916

0.1524

0.4799

0.6655

1.0000

0.6718

0.5682

0.2026

0.3123

0.0854

0.0293

0.0094

Non-epileptic hippocampus

 Time (s)

Baseline

0–0.5

0.1–0.6

0.2–0.7

0.3–0.8

0.4–0.9

0.5–1.0

0.6–1.1

0.7–1.2

0.9–1.4

1.0–1.5

1.1–1.6

1.3–1.8

 Mean RR

0.8880

0.9033

0.8405

0.7830

0.7782

0.7443

0.7943

0.9045

1.0418

1.1370

1.3300

1.1489

1.0960

 SD

0.2845

0.3465

0.3754

0.3893

0.3795

0.3705

0.3754

0.3501

0.4175

0.4225

0.3969

0.3886

0.3059

 P

1.0000

1.0000

1.0000

0.6778

0.3317

0.0127

0.0055

0.6778

0.3222

0.0127

0.0110

0.0919

0.6778