Effect of nNOS inhibitor 7-NI and GSNO on brain infarctions and neurological score. Representative TTC stained sections (#3 and 4 out of six consecutive sections from cranial to caudate region) (a), infarct area (b), infarct volume (c) and neurological score (d) at 24 h of the reperfusion after 60 min middle cerebral artery occlusion. Both 7-NI and GSNO were administered 1 h after reperfusion began. Data are presented as mean ± SD (n = 5). ***p < 0.001, **p < 0.01 vs. IR, +++p < 0.001 vs. 7-NI.