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Figure 4 | BMC Neuroscience

Figure 4

From: Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy

Figure 4

Effect of nNOS inhibitor 7-NI and GSNO on brain infarctions and neurological score. Representative TTC stained sections (#3 and 4 out of six consecutive sections from cranial to caudate region) (a), infarct area (b), infarct volume (c) and neurological score (d) at 24 h of the reperfusion after 60 min middle cerebral artery occlusion. Both 7-NI and GSNO were administered 1 h after reperfusion began. Data are presented as mean ± SD (n = 5). ***p < 0.001, **p < 0.01 vs. IR, +++p < 0.001 vs. 7-NI.

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