TY - STD TI - (2008) Smoking-attributable mortality, years of potential life lost, and productivity losses—United States, 2000–2004. MMWR Morb Mortal Wkly Rep 57: 1226–1228 ID - ref1 ER - TY - STD TI - (2013) WHO report on the global tobacco epidemiC. Ref Type: Generic ID - ref2 ER - TY - JOUR AU - Hernan, M. A. AU - Olek, M. J. AU - Ascherio, A. PY - 2001 DA - 2001// TI - Cigarette smoking and incidence of multiple sclerosis JO - Am J Epidemiol VL - 154 UR - https://doi.org/10.1093/aje/154.1.69 DO - 10.1093/aje/154.1.69 ID - Hernan2001 ER - TY - JOUR AU - Mannami, T. AU - Iso, H. AU - Baba, S. AU - Sasaki, S. AU - Okada, K. AU - Konishi, M. PY - 2004 DA - 2004// TI - Cigarette smoking and risk of stroke and its subtypes among middle-aged Japanese men and women: the JPHC Study Cohort I JO - Stroke VL - 35 UR - https://doi.org/10.1161/01.STR.0000128794.30660.e8 DO - 10.1161/01.STR.0000128794.30660.e8 ID - Mannami2004 ER - TY - JOUR AU - Rusanen, M. AU - Kivipelto, M. AU - Quesenberry, C. P. AU - Zhou, J. AU - Whitmer, R. A. PY - 2011 DA - 2011// TI - Heavy smoking in midlife and long-term risk of Alzheimer disease and vascular dementia JO - Arch Intern Med VL - 171 UR - https://doi.org/10.1001/archinternmed.2010.393 DO - 10.1001/archinternmed.2010.393 ID - Rusanen2011 ER - TY - JOUR AU - Zuo, L. AU - He, F. AU - Sergakis, G. G. AU - Koozehchian, M. S. AU - Stimpfl, J. N. AU - Rong, Y. PY - 2014 DA - 2014// TI - Interrelated role of cigarette smoking, oxidative stress, and immune response in COPD and corresponding treatments JO - Am J Physiol Lung Cell Mol Physiol VL - 307 UR - https://doi.org/10.1152/ajplung.00330.2013 DO - 10.1152/ajplung.00330.2013 ID - Zuo2014 ER - TY - JOUR AU - Messner, B. AU - Bernhard, D. PY - 2014 DA - 2014// TI - Smoking and cardiovascular disease: mechanisms of endothelial dysfunction and early atherogenesis JO - Arterioscler Thromb Vasc Biol VL - 34 UR - https://doi.org/10.1161/ATVBAHA.113.300156 DO - 10.1161/ATVBAHA.113.300156 ID - Messner2014 ER - TY - JOUR AU - Naik, P. AU - Fofaria, N. AU - Prasad, S. AU - Sajja, R. K. AU - Weksler, B. AU - Couraud, P. O. PY - 2014 DA - 2014// TI - Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe? JO - BMC Neurosci VL - 15 UR - https://doi.org/10.1186/1471-2202-15-51 DO - 10.1186/1471-2202-15-51 ID - Naik2014 ER - TY - STD TI - Sajja RK, Naik P, Cucullo L (2015) Differential cerebrovascular toxicity of various tobacco products: a regulatory perspective. J Pharmacovigil 3(1):1000e130 ID - ref9 ER - TY - JOUR AU - Hossain, M. AU - Mazzone, P. AU - Tierney, W. AU - Cucullo, L. PY - 2011 DA - 2011// TI - In vitro assessment of tobacco smoke toxicity at the BBB: do antioxidant supplements have a protective role? JO - BMC Neurosci VL - 12 UR - https://doi.org/10.1186/1471-2202-12-92 DO - 10.1186/1471-2202-12-92 ID - Hossain2011 ER - TY - JOUR AU - Ma, Q. PY - 2013 DA - 2013// TI - Role of nrf2 in oxidative stress and toxicity JO - Annu Rev Pharmacol Toxicol VL - 53 UR - https://doi.org/10.1146/annurev-pharmtox-011112-140320 DO - 10.1146/annurev-pharmtox-011112-140320 ID - Ma2013 ER - TY - JOUR AU - Pickett, G. AU - Seagrave, J. AU - Boggs, S. AU - Polzin, G. AU - Richter, P. AU - Tesfaigzi, Y. PY - 2010 DA - 2010// TI - Effects of 10 cigarette smoke condensates on primary human airway epithelial cells by comparative gene and cytokine expression studies JO - Toxicol Sci VL - 114 UR - https://doi.org/10.1093/toxsci/kfp298 DO - 10.1093/toxsci/kfp298 ID - Pickett2010 ER - TY - JOUR AU - Boyle, J. O. AU - Gumus, Z. H. AU - Kacker, A. AU - Choksi, V. L. AU - Bocker, J. M. AU - Zhou, X. K. PY - 2010 DA - 2010// TI - Effects of cigarette smoke on the human oral mucosal transcriptome JO - Cancer Prev Res (Phila) VL - 3 UR - https://doi.org/10.1158/1940-6207.CAPR-09-0192 DO - 10.1158/1940-6207.CAPR-09-0192 ID - Boyle2010 ER - TY - JOUR AU - Leeuwen, D. M. AU - Gottschalk, R. W. AU - Herwijnen, M. H. AU - Moonen, E. J. AU - Kleinjans, J. C. AU - Delft, J. H. PY - 2005 DA - 2005// TI - Differential gene expression in human peripheral blood mononuclear cells induced by cigarette smoke and its constituents JO - Toxicol Sci VL - 86 UR - https://doi.org/10.1093/toxsci/kfi168 DO - 10.1093/toxsci/kfi168 ID - Leeuwen2005 ER - TY - JOUR AU - Wright, W. R. AU - Parzych, K. AU - Crawford, D. AU - Mein, C. AU - Mitchell, J. A. AU - Paul-Clark, M. J. PY - 2012 DA - 2012// TI - Inflammatory transcriptome profiling of human monocytes exposed acutely to cigarette smoke JO - PLoS ONE VL - 7 UR - https://doi.org/10.1371/journal.pone.0030120 DO - 10.1371/journal.pone.0030120 ID - Wright2012 ER - TY - JOUR AU - Weksler, B. AU - Romero, I. A. AU - Couraud, P. O. PY - 2013 DA - 2013// TI - The hCMEC/D3 cell line as a model of the human blood brain barrier JO - Fluids Barriers CNS VL - 10 UR - https://doi.org/10.1186/2045-8118-10-16 DO - 10.1186/2045-8118-10-16 ID - Weksler2013 ER - TY - JOUR AU - Hayes, J. D. AU - Dinkova-Kostova, A. T. PY - 2014 DA - 2014// TI - The Nrf2 regulatory network provides an interface between redox and intermediary metabolism JO - Trends Biochem Sci VL - 39 UR - https://doi.org/10.1016/j.tibs.2014.02.002 DO - 10.1016/j.tibs.2014.02.002 ID - Hayes2014 ER - TY - JOUR AU - Johansson, I. AU - Ingelman-Sundberg, M. PY - 2011 DA - 2011// TI - Genetic polymorphism and toxicology—with emphasis on cytochrome p450 JO - Toxicol Sci VL - 120 UR - https://doi.org/10.1093/toxsci/kfq374 DO - 10.1093/toxsci/kfq374 ID - Johansson2011 ER - TY - JOUR AU - Thum, T. AU - Erpenbeck, V. J. AU - Moeller, J. AU - Hohlfeld, J. M. AU - Krug, N. AU - Borlak, J. PY - 2006 DA - 2006// TI - Expression of xenobiotic metabolizing enzymes in different lung compartments of smokers and nonsmokers JO - Environ Health Perspect VL - 114 ID - Thum2006 ER - TY - JOUR AU - Rebrin, I. AU - Sohal, R. S. PY - 2008 DA - 2008// TI - Pro-oxidant shift in glutathione redox state during aging JO - Adv Drug Deliv Rev VL - 60 UR - https://doi.org/10.1016/j.addr.2008.06.001 DO - 10.1016/j.addr.2008.06.001 ID - Rebrin2008 ER - TY - JOUR AU - Brzoska, K. AU - Stepkowski, T. M. AU - Kruszewski, M. PY - 2014 DA - 2014// TI - Basal PIR expression in HeLa cells is driven by NRF2 via evolutionary conserved antioxidant response element JO - Mol Cell Biochem VL - 389 UR - https://doi.org/10.1007/s11010-013-1931-0 DO - 10.1007/s11010-013-1931-0 ID - Brzoska2014 ER - TY - JOUR AU - Bowie, A. AU - O’Neill, L. A. PY - 2000 DA - 2000// TI - Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries JO - Biochem Pharmacol VL - 59 UR - https://doi.org/10.1016/S0006-2952(99)00296-8 DO - 10.1016/S0006-2952(99)00296-8 ID - Bowie2000 ER - TY - JOUR AU - Khanna, A. AU - Guo, M. AU - Mehra, M. AU - Royal, W. PY - 2013 DA - 2013// TI - Inflammation and oxidative stress induced by cigarette smoke in Lewis rat brains JO - J Neuroimmunol VL - 254 UR - https://doi.org/10.1016/j.jneuroim.2012.09.006 DO - 10.1016/j.jneuroim.2012.09.006 ID - Khanna2013 ER - TY - JOUR AU - Boutten, A. AU - Goven, D. AU - Artaud-Macari, E. AU - Boczkowski, J. AU - Bonay, M. PY - 2011 DA - 2011// TI - NRF2 targeting: a promising therapeutic strategy in chronic obstructive pulmonary disease JO - Trends Mol Med VL - 17 UR - https://doi.org/10.1016/j.molmed.2011.02.006 DO - 10.1016/j.molmed.2011.02.006 ID - Boutten2011 ER - TY - JOUR AU - Mann, G. E. AU - Niehueser-Saran, J. AU - Watson, A. AU - Gao, L. AU - Ishii, T. AU - Winter, P. PY - 2007 DA - 2007// TI - Nrf2/ARE regulated antioxidant gene expression in endothelial and smooth muscle cells in oxidative stress: implications for atherosclerosis and preeclampsia JO - Sheng Li Xue Bao VL - 59 ID - Mann2007 ER - TY - JOUR AU - Iizuka, T. AU - Ishii, Y. AU - Itoh, K. AU - Kiwamoto, T. AU - Kimura, T. AU - Matsuno, Y. PY - 2005 DA - 2005// TI - Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema JO - Genes Cells VL - 10 UR - https://doi.org/10.1111/j.1365-2443.2005.00905.x DO - 10.1111/j.1365-2443.2005.00905.x ID - Iizuka2005 ER - TY - JOUR AU - Guan, S. P. AU - Tee, W. AU - Ng, D. S. AU - Chan, T. K. AU - Peh, H. Y. AU - Ho, W. E. PY - 2013 DA - 2013// TI - Andrographolide protects against cigarette smoke-induced oxidative lung injury via augmentation of Nrf2 activity JO - Br J Pharmacol VL - 168 UR - https://doi.org/10.1111/bph.12054 DO - 10.1111/bph.12054 ID - Guan2013 ER - TY - JOUR AU - Sussan, T. E. AU - Rangasamy, T. AU - Blake, D. J. AU - Malhotra, D. AU - El-Haddad, H. AU - Bedja, D. PY - 2009 DA - 2009// TI - Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice JO - Proc Natl Acad Sci USA VL - 106 UR - https://doi.org/10.1073/pnas.0804333106 DO - 10.1073/pnas.0804333106 ID - Sussan2009 ER - TY - STD TI - Ghosh C, Gonzalez-Martinez J, Hossain M, Cucullo L, Fazio V, Janigro D et al (2010) Pattern of P450 expression at the human blood-brain barrier: Roles of epileptic condition and laminar flow. Epilepsia ID - ref29 ER - TY - JOUR AU - Paine, A. AU - Eiz-Vesper, B. AU - Blasczyk, R. AU - Immenschuh, S. PY - 2010 DA - 2010// TI - Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential JO - Biochem Pharmacol VL - 80 UR - https://doi.org/10.1016/j.bcp.2010.07.014 DO - 10.1016/j.bcp.2010.07.014 ID - Paine2010 ER - TY - JOUR AU - Haines, D. D. AU - Lekli, I. AU - Teissier, P. AU - Bak, I. AU - Tosaki, A. PY - 2012 DA - 2012// TI - Role of haeme oxygenase-1 in resolution of oxidative stress-related pathologies: focus on cardiovascular, lung, neurological and kidney disorders JO - Acta Physiol (Oxf) VL - 204 UR - https://doi.org/10.1111/j.1748-1716.2011.02387.x DO - 10.1111/j.1748-1716.2011.02387.x ID - Haines2012 ER - TY - STD TI - Brzoska K, Stepkowski TM, Kruszewski M (2011) Putative proto-oncogene Pir expression is significantly up-regulated in the spleen and kidney of cytosolic superoxide dismutase-deficient mice. Redox Rep 16:129–133 ID - ref32 ER - TY - JOUR AU - Liu, F. AU - Rehmani, I. AU - Esaki, S. AU - Fu, R. AU - Chen, L. AU - Serrano, V. PY - 2013 DA - 2013// TI - Pirin is an iron-dependent redox regulator of NF-kappaB JO - Proc Natl Acad Sci USA VL - 110 UR - https://doi.org/10.1073/pnas.1221743110 DO - 10.1073/pnas.1221743110 ID - Liu2013 ER - TY - JOUR AU - Yang, H. AU - Magilnick, N. AU - Ou, X. AU - Lu, S. C. PY - 2005 DA - 2005// TI - Tumour necrosis factor alpha induces co-ordinated activation of rat GSH synthetic enzymes via nuclear factor kappaB and activator protein-1 JO - Biochem J VL - 391 UR - https://doi.org/10.1042/BJ20050379 DO - 10.1042/BJ20050379 ID - Yang2005 ER - TY - JOUR AU - Yang, H. AU - Magilnick, N. AU - Lee, C. AU - Kalmaz, D. AU - Ou, X. AU - Chan, J. Y. PY - 2005 DA - 2005// TI - Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1 JO - Mol Cell Biol VL - 25 UR - https://doi.org/10.1128/MCB.25.14.5933-5946.2005 DO - 10.1128/MCB.25.14.5933-5946.2005 ID - Yang2005 ER - TY - JOUR AU - Kunsch, C. AU - Lang, R. K. AU - Rosen, C. A. AU - Shannon, M. F. PY - 1994 DA - 1994// TI - Synergistic transcriptional activation of the IL-8 gene by NF-kappa B p65 (RelA) and NF-IL-6 JO - J Immunol VL - 153 ID - Kunsch1994 ER - TY - JOUR AU - Barr, J. AU - Sharma, C. S. AU - Sarkar, S. AU - Wise, K. AU - Dong, L. AU - Periyakaruppan, A. PY - 2007 DA - 2007// TI - Nicotine induces oxidative stress and activates nuclear transcription factor kappa B in rat mesencephalic cells JO - Mol Cell Biochem VL - 297 UR - https://doi.org/10.1007/s11010-006-9333-1 DO - 10.1007/s11010-006-9333-1 ID - Barr2007 ER - TY - JOUR AU - Messner, B. AU - Bernhard, D. PY - 2014 DA - 2014// TI - Smoking and cardiovascular disease: mechanisms of endothelial dysfunction and early atherogenesis JO - Arterioscler Thromb Vasc Biol VL - 34 UR - https://doi.org/10.1161/ATVBAHA.113.300156 DO - 10.1161/ATVBAHA.113.300156 ID - Messner2014 ER - TY - JOUR AU - Giunzioni, I. AU - Bonomo, A. AU - Bishop, E. AU - Castiglioni, S. AU - Corsini, A. AU - Bellosta, S. PY - 2014 DA - 2014// TI - Cigarette smoke condensate affects monocyte interaction with endothelium JO - Atherosclerosis VL - 234 UR - https://doi.org/10.1016/j.atherosclerosis.2014.03.029 DO - 10.1016/j.atherosclerosis.2014.03.029 ID - Giunzioni2014 ER - TY - JOUR AU - Lagente, V. AU - Planquois, J. M. AU - Leclerc, O. AU - Schmidlin, F. AU - Bertrand, C. P. PY - 2008 DA - 2008// TI - Oxidative stress is an important component of airway inflammation in mice exposed to cigarette smoke or lipopolysaccharide JO - Clin Exp Pharmacol Physiol VL - 35 UR - https://doi.org/10.1111/j.1440-1681.2007.04848.x DO - 10.1111/j.1440-1681.2007.04848.x ID - Lagente2008 ER - TY - JOUR AU - Li, J. R. AU - Zhou, W. X. AU - Zhao, Z. X. AU - Gao, J. M. PY - 2014 DA - 2014// TI - Differential expression of the inflammation-associated chemokines/cytokines in mouse lung after exposure to cigarette smoke and smoking cessation JO - Zhongguo Yi Xue Ke Xue Yuan Xue Bao VL - 36 ID - Li2014 ER - TY - JOUR AU - Fischer, S. AU - Wobben, M. AU - Marti, H. H. AU - Renz, D. AU - Schaper, W. PY - 2002 DA - 2002// TI - Hypoxia-induced hyperpermeability in brain microvessel endothelial cells involves VEGF-mediated changes in the expression of zonula occludens-1 JO - Microvasc Res VL - 63 UR - https://doi.org/10.1006/mvre.2001.2367 DO - 10.1006/mvre.2001.2367 ID - Fischer2002 ER - TY - JOUR AU - Sajja, R. K. AU - Prasad, S. AU - Cucullo, L. PY - 2014 DA - 2014// TI - Impact of altered glycaemia on blood-brain barrier endothelium: an in vitro study using the hCMEC/D3 cell line JO - Fluids Barriers CNS VL - 11 UR - https://doi.org/10.1186/2045-8118-11-8 DO - 10.1186/2045-8118-11-8 ID - Sajja2014 ER - TY - JOUR AU - Sobczak, A. AU - Golka, D. AU - Szoltysek-Boldys, I. PY - 2004 DA - 2004// TI - The effects of tobacco smoke on plasma alpha- and gamma-tocopherol levels in passive and active cigarette smokers JO - Toxicol Lett VL - 151 UR - https://doi.org/10.1016/j.toxlet.2004.03.010 DO - 10.1016/j.toxlet.2004.03.010 ID - Sobczak2004 ER - TY - JOUR AU - Dietrich, M. AU - Block, G. AU - Norkus, E. P. AU - Hudes, M. AU - Traber, M. G. AU - Cross, C. E. PY - 2003 DA - 2003// TI - Smoking and exposure to environmental tobacco smoke decrease some plasma antioxidants and increase gamma-tocopherol in vivo after adjustment for dietary antioxidant intakes JO - Am J Clin Nutr VL - 77 ID - Dietrich2003 ER - TY - JOUR AU - Willcox, J. K. AU - Ash, S. L. AU - Catignani, G. L. PY - 2004 DA - 2004// TI - Antioxidants and prevention of chronic disease JO - Crit Rev Food Sci Nutr VL - 44 UR - https://doi.org/10.1080/10408690490468489 DO - 10.1080/10408690490468489 ID - Willcox2004 ER - TY - JOUR AU - Masubuchi, T. AU - Koyama, S. AU - Sato, E. AU - Takamizawa, A. AU - Kubo, K. AU - Sekiguchi, M. PY - 1998 DA - 1998// TI - Smoke extract stimulates lung epithelial cells to release neutrophil and monocyte chemotactic activity JO - Am J Pathol VL - 153 UR - https://doi.org/10.1016/S0002-9440(10)65704-5 DO - 10.1016/S0002-9440(10)65704-5 ID - Masubuchi1998 ER - TY - JOUR AU - Ambrose, J. A. AU - Barua, R. S. PY - 2004 DA - 2004// TI - The pathophysiology of cigarette smoking and cardiovascular disease: an update JO - J Am Coll Cardiol VL - 43 UR - https://doi.org/10.1016/j.jacc.2003.12.047 DO - 10.1016/j.jacc.2003.12.047 ID - Ambrose2004 ER - TY - JOUR AU - Abbruscato, T. J. AU - Lopez, S. P. AU - Mark, K. S. AU - Hawkins, B. T. AU - Davis, T. P. PY - 2002 DA - 2002// TI - Nicotine and cotinine modulate cerebral microvascular permeability and protein expression of ZO-1 through nicotinic acetylcholine receptors expressed on brain endothelial cells JO - J Pharm Sci VL - 91 UR - https://doi.org/10.1002/jps.10256 DO - 10.1002/jps.10256 ID - Abbruscato2002 ER - TY - JOUR AU - Hawkins, B. T. AU - Abbruscato, T. J. AU - Egleton, R. D. AU - Brown, R. C. AU - Huber, J. D. AU - Campos, C. R. PY - 2004 DA - 2004// TI - Nicotine increases in vivo blood-brain barrier permeability and alters cerebral microvascular tight junction protein distribution JO - Brain Res VL - 1027 UR - https://doi.org/10.1016/j.brainres.2004.08.043 DO - 10.1016/j.brainres.2004.08.043 ID - Hawkins2004 ER - TY - JOUR AU - Lockman, P. R. AU - McAfee, G. AU - Geldenhuys, W. J. AU - Schyf, C. J. AU - Abbruscato, T. J. AU - Allen, D. D. PY - 2005 DA - 2005// TI - Brain uptake kinetics of nicotine and cotinine after chronic nicotine exposure JO - J Pharmacol Exp Ther VL - 314 UR - https://doi.org/10.1124/jpet.105.085381 DO - 10.1124/jpet.105.085381 ID - Lockman2005 ER - TY - JOUR AU - Livak, K. J. AU - Schmittgen, T. D. PY - 2001 DA - 2001// TI - Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method JO - Methods VL - 25 UR - https://doi.org/10.1006/meth.2001.1262 DO - 10.1006/meth.2001.1262 ID - Livak2001 ER -