From: Targeted inhibition of the Shroom3–Rho kinase protein–protein interaction circumvents Nogo66 to promote axon outgrowth
Total # compounds screened
20,000
Hits from primary screen
180 (0.9%)
Dose response
36 (0.18%)
Available for re-supply
32 (0.16%)
Confirmed inhibitors
27 (0.14%)
IC50 <30 μM
9 (0.05%)
Enhanced neurite outgrowth
1 (0.005%)