Figure 2From: Targeted inhibition of the Shroom3–Rho kinase protein–protein interaction circumvents Nogo66 to promote axon outgrowthCCG-17444 inhibits the Shroom3–ROCK II protein–protein interaction. a Chemical structure of CCG-17444 (Chem ID: 2816053). b CCG-17444 inhibits the Shroom3–ROCK II interaction with an IC50 of 12.4 ± 2.3 (IC50 ± SEM, n = 3).Back to article page