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Figure 8 | BMC Neuroscience

Figure 8

From: Hydrogen improves neurological function through attenuation of blood–brain barrier disruption in spontaneously hypertensive stroke-prone rats

Figure 8

Effect of hydrogen-rich water (HRW) on the activity of matrix metalloproteinases (MMPs) in the brain. Representative images of gelatin zymography and quantification of the relative optical density of MMP-2 and MMP-9. In the cortex, there were no significant differences in MMP-2 and MMP-9 activities (P = 0.84 and 0.20, respectively). In the hippocampus, MMP-9 activity was significantly greater in the control group compared to the HRW group (P < 0.001), whereas there was no significant difference in MMP-2 activity (P = 0.84). Data were analyzed by an unpaired t-test. Values are expressed as mean ± SEM. n = 6 in each group. ***P < 0.001 vs. control group.

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