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Figure 8 | BMC Neuroscience

Figure 8

From: Simulation of alcohol action upon a detailed Purkinje neuron model and a simpler surrogate model that runs >400 times faster

Figure 8

In the full and reduced Purkinje neuron models, an introduced ERG potassium current can repolarise dendritic spikes in the absence of the BK potassium current. BK density is set to 0 in all compartments and ERG is introduced into the dendrite compartments, at an equivalent density (refer Results) for the reduced and full model. A, Membrane potential at the soma of the 2 compartment model. B, Membrane potential at the dendrite of the 2 compartment model. C, Membrane potential at the soma of the 1089 compartment model. D, Membrane potential at the dendrite of the 1089 compartment model (spiny compartment 1001).

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