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Figure 2 | BMC Neuroscience

Figure 2

From: Time dynamics of protein complexes in the AD11 transgenic mouse model for Alzheimer’s disease like pathology

Figure 2

Correlation in Parvulin complex at 1 month of age. Whole correlation matrices of Parvulin-associated pre-rRNP complex in AD11 and control mice (top and center), and the difference matrix (bottom) at 1 month of age. The gene symbols are along the matrix. Correlation values go from −1.0 (red) to +1.0 (green). The correlation structure is globally very different, in particular the red arrows in the difference matrix highlight the Ddx5 gene row and column that show a strong anti-correlation in AD11 compared to control. The protein complex interaction network is shown on the bottom right, as obtained from the StringDB online tool. The Ddx5 protein appears as very poorly connected to the network.

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