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Figure 7 | BMC Neuroscience

Figure 7

From: Disrupting monotony during social isolation stress prevents early development of anxiety and depression like traits in male rats

Figure 7

Protein expression study by western blotting. i) Representative western blots showing expression of pIGF-1R, pCREB and β-Actin. Densitometric results depict the changes in expression of (ii) pIGF-1R, (iii) pCREB and (iv) β-Actin following exposure to monotony stress, PCPA administration and novel object intervention during isolation. Values are expressed as percentage change in protein expression considering mean OD of PHNO group to be 100%. ‘a’ denotes p ≤ 0.01 when compared to PHNO group, ‘b’ denotes p ≤ 0.01 when compared to PH, ‘c’ denotes p ≤ 0.01 when compared to PHNOPCPA group, ‘d’ denotes p ≤ 0.01 when compared to PHPCPA group and ‘e’ denotes p ≤ 0.01 when compared to SH group and ‘f’ denotes p ≤ 0.01 when compared with SHNO group.

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