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Figure 1 | BMC Neuroscience

Figure 1

From: The protective effect of growth hormone on Cu/Zn superoxide dismutase-mutant motor neurons

Figure 1

PI3-kinase or MAP-kinase inhibitor treatment and activation of pAkt and pERK by GH. Increased viability of A4V was reduced by W13 (p = 0.039) (A). Increased viability of G93A was reduced by treatment with PD098059, a MAP-kinase inhibitor (p = 0.038) (B). GH was applied at 0.004 I.U/ml and active pAkt and pERK forms were identified 5, 10, and 20 min later. The change in levels of pAkt and pERK in A4V and G93A cell lines at different time points were analyzed (C). Results are expressed as mean values and SD (*p < 0.05).

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