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Figure 2 | BMC Neuroscience

Figure 2

From: Noise alters guinea pig’s blood-labyrinth barrier ultrastructure and permeability along with a decrease of cochlear Claudin-5 and Occludin

Figure 2

The ultrastructure of cochlea from control (A,B), NE 2d (A’,B’) and NE 4 h (A”,B”) groups as well as the distribution of lanthanum nitrate particles from Control (C), NE 2d (C’) and NE 4 h (C”) groups examined with TEM. A) Normal ultrastructure of BLB showing PC, EC and fp/PC. B) Normal ultrastructure of TJ. C) LNPs were restrained inside the cochlear vessels from a control animal. A’) Ultrastructure of BLB showing PC, EC and fp/PC after NE 2d. B’) Ultrastructure of TJ after NE 2d. C’) LNPs entered into the tissue after NE 2d. A”) Ultrastructure of BLB showing PC, EC and fp/PC after NE 4 h. B”) Ultrastructure of TJ after NE 4 h. C”) LNPs entered into the tissue after NE 4 h. Arrows in B, B’ and B” indicate TJ. BL, basal lamina; CV, capillary vessel; EC, endothelial cells; fp, pericyte foot; LNPs, lanthanum nitrate particles; PC, pericytes; RBC, red blood cells. Scale bar in A, A’ and A” = 500 nm; in the other panels = 100 nm.

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