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Figure 8 | BMC Neuroscience

Figure 8

From: Ability of naringenin, a bioflavonoid, to activate M-type potassium current in motor neuron-like cells and to increase BKCa-channel activity in HEK293T cells transfected with α-hSlo subunit

Figure 8

Effect of NGEN on whole-cell I K(Ca) in α -hSlo -expressing HEK293T cells. In these experiments, cells were bathed in normal Tyrode’s solution containing 1.8 mM CaCl2. (A) Current traces in response to membrane depolarization from 0 to +50 mV. The upper part indicates the voltage protocol used. a: control; b: 3 μM NGEN; c: 10 μM NGEN; and d: 30 μM NGEN. (B) Summary of the data showing effects of NGEN, NGEN plus verruculogen (Verr; 1 μM) and NGEN plus iberiotoxin (Iber; 200 nM) on I K(Ca) amplitude in these cells (mean ± SEM; n = 10-13 for each bar). *Significantly different from control. **Significantly different from NGEN (30 μM) alone group.

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BMC Neuroscience

ISSN: 1471-2202

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