Figure 7
From: Critical role of extracellularly secreted neuronal pentraxin 1 in ischemic neuronal death
Extracellular release of NP1 protein following OGD enhances interaction between NP1 and GluR1 at the synaptic sites. Live immunostaining of DIV 12 primary cortical neurons with NP1 and GluR1 antibodies following OGD (4 h). Immunofluorescence microscopy and merged images show increased number of NP1 (red) and GluR1 (green) co-localized clusters (yellow) at cortical dendrites and axons. Representative images are shown, n = 6, Scale, 100 μm.