Protein expression of inflammatory cytokines and iNOS was decreased in LPS-activated microglial cells following treatment with E, S and E + S. The expression levels of TNF-α, IL-1β and iNOS in LPS-activated microglial cells are depressed significantly following treatment with E, S and E + S. Significant differences in protein levels between LPS and drugs used groups are expressed as *p < 0.05. TNF-α and iNOS protein expression level in LPS + S group and LPS + E + S group was markedly suppressed when compared with the LPS + E group. Furthermore, the expression of TNF-α in LPS + E + S BV-2 cells was significantly lower than other groups. Significant differences in protein levels are expressed as #p < 0.05 and △p <0.01. The values represent the mean ± SD in triplicate.