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Table 1 Sojourn times and Normalized Transition Rates (NTR) in the onset phase

From: Chronic escitalopram treatment attenuated the accelerated rapid eye movement sleep transitions after selective rapid eye movement sleep deprivation: a model-based analysis using Markov chains

Onset phase (starting at light onset; 0-2000 s)
Group WAKE SLEEP
  Sojourn time (s) L U Sojourn time (s) L U
RD-SSRI 212.102 155.104 290.046 25.467 16.864 38.460
HC-SSRI 254.713 186.264 348.315 14.176 * 9.387 21.408
RD-VEH 374.026 * 264.968 527.973 21.609 13.941 33.493
HC-VEH 174.131 127.337 238.122 35.239 23.334 53.216
  WAKE→SLEEP SLEEP→WAKE
  NTR L U NTR L U
RD-SSRI 0.821 0.587 1.147 1.384 0.958 1.999
HC-SSRI 0.684 * 0.489 0.956 2.486 * 1.791 3.450
RD-VEH 0.465 * 0.323 0.670 1.631 * 1.135 2.343
  1. Sojourn time: the estimated mean of the average time span of an event;
  2. Normalized Transition Rate (NTR): relative transition rate compared to the HC-VEH group (NTR of the HC-VEH group is 1);
  3. * p < 0.05, significant effect compared to the HC-VEH group;
  4. L and U: lower and the upper limits of the corresponding 95% confidence interval, respectively;
  5. Normalized Transition Rate (NTR): relative transition rate compared to the HC-VEH group (NTR of the HC-VEH group is 1);
  6. Groups: home cage plus chronic vehicle treatment (HC-VEH); home cage plus chronic escitalopram treatment (HC-SSRI); REM sleep deprivation plus chronic vehicle treatment (RD-VEH); REM sleep deprivation plus chronic escitalopram treatment (RD-SSRI).