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Figure 3 | BMC Neuroscience

Figure 3

From: Genetic deletion of calcium/calmodulin-dependent protein kinase kinase β (CaMKK β) or CaMK IV exacerbates stroke outcomes in ovariectomized (OVXed) female mice

Figure 3

Loss of CaMKK β or CaMK IV increased gelatinase activity and reduced collagen IV levels 6 hours after stroke. A and B, representative bands of MMP-9 expression assessed by gelatin zymograpy in CaMKK β/CaMK IV KO mice. C and D, quantification of MMP-9 expression, n = 3 for each group. Data were normalized to corresponding WT stroke mice in each strain. E and F, representative of collagen IV by Western blot in CaMKK β/CaMK IV KO mice. G and H, quantification of collagen IV expression, n = 3 sham/n = 4 stroke. Data were normalized to corresponding WT sham. #P < 0.05 compared to WT stroke; Data were presented as mean ± SEM.

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