Figure 2

A) Localization of GPR125 using qPCR in mouse brain and peripheral tissues. Values are expressed relative to the minimum expression value for this analysis (colliculus). B) GPR125 expression was not changed following induction of an inflammatory response via LPS injection. C) GPR125 expression was affected by TBI. GPR125 in the choroid plexus was upregulated at 4 h after injury while the upregulation in the hippocampus did not occur until 1 day post-TBI, suggesting a role of the CSF pathways in post-traumatic regulation of GPR125 expression in the choroid plexus and hippocampus.