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Table 1 Fgf2 exon 3 -/- mice show a decrease in cortical neuron and glial cell populations

From: Decrease in excitatory neurons, astrocytes and proliferating progenitors in the cerebral cortex of mice lacking exon 3 from the Fgf2 gene

 

Cell number

 
 

Wild type

Fgf2 -/-

% of control

Total NeuN+ cells (106)

1.7 ± 0.04

1.3 ± 0.09*

77

Total GFAP+ cells (106)

1.0 ± 0.08

0.7 ± 0.06*

66

Density NeuN+ cells (103 /mm3)

53 ± 4.8

33 ± 3.3**

63

Density GFAP+ cells (103 /mm3)

33 ± 3.6

19 ± 0.33*

58

  1. Cell number was assessed by stereological analyses. N = 4 per group,*p < 0.05, **p < 0.01 (Student's t-test).
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BMC Neuroscience

ISSN: 1471-2202

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