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Table 2 Clinical data for ExpG cynomolgus macaques.

From: Bioinformatic and statistical analysis of the optic nerve head in a primate model of ocular hypertension

Macaque

IOP, control eye (mm Hg)

IOP, ExpG eye (mm Hg)

Duration elevated IOP (weeks/days)

C/D ratio control eye

C/D ratio ExpG eye

Axon loss (%)

Evaluation

577

15.0 ± 2.6

24.7 ± 7.5

10.9/76

0.25

0.4

21

Mild

578

17.1 ± 2.4

33.2 ± 10.3

33.4/234

0.25

0.5

25

Mild

579

19.1 ± 1.8

28.1 ± 4.5

12.6/88

0.4

0.7

32

Mild

566

15.0 ± 2.7

27.4 ± 18.5

6.1/43

0.25

0.8

74

Advanced

529

13.8 ± 2.3

36.0 ± 18.5

7.3/51

0.2

0.9

59

Moderate

  1. Experimental paired cynomolgus macaques used for the microarray analysis and qRT-PCR verification of the present study.
  2. IOP measurements represent mean ± SD. 'Axon loss' and 'Evaluation' are as defined in Methods.
  3. IOP = Intraocular pressure. C/D ratio = cup/disk ratio. M = male; F = female.