Time course of apoptosis and necrosis of post-hypoxic neuronal cells in direct co-cultures with tMNC, CD133+ and CD133-. Box plots showing time course of apoptosis (A) and necrosis/late apoptosis (B) in direct co-cultures of post-hypoxic neuronal cells with tMNC, CD133- or CD133+ (colored plots). Grey boxes display the development of cell death in post-hypoxic neuronal cells directly after hypoxic pre-cultivation of SH-SY5Y cells (Day 0) and 1–3 days post-hypoxia. The ordinate represents the percentage of apoptotic and necrotic cells, respectively. Rates of apoptosis and necrosis were calculated in relation to the total number of SH-SY5Y cells.