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Figure 1 | BMC Neuroscience

Figure 1

From: Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice

Figure 1

Progressive neurological deficits. (A, B) Narrow bridges. Mice were trained for three days. The latency to cross the bridge (A) and the number of foot slips (B) on a round wood beam (11 mm) were recorded (PS-NA, n = 10; WT, n = 10). PS-NA mice [open triangles] made significantly more foot slips and slower latency than WT [black squares] (*p < 0.05, **p < 0.01, ***p < 0.001). (C) Locomotor test at 18 wks. The mice were placed in an activity chamber for 120 min and locomotor activity was recorded in 5 min intervals (PS-NA, n = 5; WT, n = 5). PS-NA [open triangles] mice showed progressive failure to habituate compared to WT [black squares] mice.

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