The effects of CGRP on the firing rate of a responsive temperature insensitive neuron. A, shows the firing rate of this neuron in response to CGRP. The beginning of a CGRP exposure is indicated by the arrow. In B, firing rate is plotted as a function of temperature. In C, the average firing rates are plotted for one minute segments of activity during Baseline (3.7 ± 0.1 impulses.s-1), CGRP (5.6 ± 0.1 impulses.s-1), and Washout (3.7 ± 0.1 impulses.s-1). For the bar graphs in C, standard error bars may be difficult to visualize.