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Figure 7 | BMC Neuroscience

Figure 7

From: Sub region-specific modulation of synchronous neuronal burst firing after a kainic acid insult in organotypic hippocampal cultures

Figure 7

CA1 hyperexcitability is maintained 7 days after KA insult. (A) Schematic showing electrode placement. Dotted line indicates surgical separation of CA3. (B) Example of synchronized neuronal burst firing under Mg2+-free conditions at the 7 day post KA time-point (C) IBI in cultures 7 days after KA insult and age-matched controls prior to and after surgical separation of CA3 (* p < 0.05, n = 6, ANOVA). (D) Burst duration in CA1 7 days after KA treatment, prior to and after CA3 deafferentation (* p < 0.05, n = 6, ANOVA). Closed bars are controls, open bars are 8 h KA-treated +7d.

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