Figure 6From: Dysfunctional GABAergic inhibition in the prefrontal cortex leading to "psychotic" hyperactivationA schematic diagram of the model. The PFC contains pyramidal neurons and GABAergic interneurons (chandelier cells (C) and others (N)), which are connected reciprocally and have also self-innervations. All populations of neurons are under dopaminergic modulation via D1 receptors. The transient input to the pyramidal neurons triggers the dynamics of the circuit.Back to article page