Figure 2
From: Dysfunctional GABAergic inhibition in the prefrontal cortex leading to "psychotic" hyperactivation
Nullclines of the state variables of the pyramidal neurons and the GABAergic interneurons other than chandelier cells for three different levels of D1 receptor activation. A: z = 3.0; B: z = 5.0; C: z = 7.0. The nullcline for the pyramidal neurons (dx p /dt = 0) is depicted in blue and the nullcline for the GABAergic interneurons (dx n /dt = 0) is depicted in green. The inset (A1) is an enlargement view of A. The circles indicate stable fixed points and the crosses indicate unstable fixed points. The arrows show the direction of state transition toward one of the stable fixed points.