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Table 1 Environmental enrichment did not ameliorate the effects of the HD mutation on body and brain weight at 9 months of age. The HD transgene affected both body weight (P < 0.001) and brain weight (P < 0.001), relative to WT littermates. NE: non-enriched (standard housed); EE: environmentally enriched.

From: Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease

 

WT

HD

 

EE

NE

EE

NE

Body weight (grams)

36.74 ± 1.75

40.02 ± 2.24

20.73 ± 0.56

21.24 ± 0.98

Brain weight (grams)

0.44 ± 0.013

0.45 ± 0.008

0.34 ± 0.013

0.36 ± 0.012