Table 1 Transgenic efficiency after injection of lentiviral vectors carrying the APPSw/Ind double mutation under control of the ubiquitin-C promoter in Fischer 344 rat zygotes.
Zygotes injected | Embryos transferred | Live pups born | Transgenic pups | Germline transgenic |
|---|---|---|---|---|
168 | 156 (93%) | 18 (12%) | 4 (22%) | 2 (50%) |