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Figure 5 | BMC Neuroscience

Figure 5

From: Development of transgenic rats producing human β-amyloid precursor protein as a model for Alzheimer's disease: Transgene and endogenous APP genes are regulated tissue-specifically

Figure 5

Gene expression differences among organs obtained from APP21, APP31 and WT rats. A. The expression of APP genes is normalized by dividing the net intensity of APP bands by the 18S rRNA bands. ** represent significantly greater APP expression in APP21 compared to APP31 and WT rats (P < 0.05); * represents significantly greater APP expression in APP31 compared to WT rats (P < 0.05). B. APP expression-difference between APP21 and APP31 rats compared to WT animals. The values were obtained by dividing the APP expression in each organ (B: Brain, H: Heart, K: Kidney, Li: Liver, Lu: Lung) by APP expression in WT rats.

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BMC Neuroscience

ISSN: 1471-2202

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