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Figure 1 | BMC Neuroscience

Figure 1

From: Development of transgenic rats producing human β-amyloid precursor protein as a model for Alzheimer's disease: Transgene and endogenous APP genes are regulated tissue-specifically

Figure 1

Comparison of promoters following lentivirus injection in rat brain. Lentiviruses were stereotaxically injected into rat hippocampus and examined after three months. A. eGFP expression driven by the ubiquitin-C promoter (Ubi-C) was consistently superior to that of other promoters, including the platelet-derived growth factor promoter (PDGF) and cytomegalovirus. Lower panels show representative higher power images of eGFP driven by Ubi-C- (B), cytomegalovirus- (C), and PDGF- (D) promoters in lentivirus/eGFP-injected rats.

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BMC Neuroscience

ISSN: 1471-2202

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