Figure 7From: Alterations in the Notch4 pathway in cerebral endothelial cells by the HIV aspartyl protease inhibitor, nelfinavirEffects of Vitamin E on PI-induced changes in Notch 4 expression and processing. Western analyses of CEC exposed to 5 μM saquinavir (SQV), indinavir (INV), nelfinavir (NFV), and ritonavir (RTV) for 48 h with or without Vitamin E pre-treatment (VitE). A) Expression levels of total Notch 4, B) percentage of total Notch 4 processed to NICD. * p ≤ 0.005 by one way ANOVA with Dunnett's post hoc test when compared to untreated control. Graphs reflect results from three separate experiments.Back to article page