Figure 12

NFV does not interfere with angiogenic capacity in CEC grown in a collagen matrix. A) Representative image of untreated CEC in matrigel forming aring structure and branching. B-D) Results from Matrigel angiogenesis assay showing key elements of angiogenic behavior in CEC treated with Nelfinavir (NFV), vitamin E (VE), NFV/VE, or untreated control, B) Number of rings formed, *p ≤ 0.0001, C) Number of branch points, *p ≤ 0.0001, D) Extension lengths, *p ≤ 0.01. Results are from at least 10 separate fields of view in three separate experiments. P value was calculated by one way ANOVA with Dunnett's post hoc test when compared to untreated control.