Figure 1From: Alterations in the Notch4 pathway in cerebral endothelial cells by the HIV aspartyl protease inhibitor, nelfinavirHIV PIs do not affect cell viability in CEC. Trypan blue staining for CEC viability was conducted after treatment with saquinavir (SQV), indinavir (INV), nelfinavir (NFV), or Ritonavir (RTV) for 24 h at 0, 0.5, 1, 5 and 25 μM dose concentrations. Trypan blue staining was conducted for CEC viability after treatment with 5 μM saquinavir (SQV), 5 μM indinavir (INV), 5 μM nelfinavir (NFV), 5 μM ritonavir (RTV), or 5 μM INV/1 μM RTV for 24, 48, 72 and 96 h. Percent cell death was calculated for each condition.Back to article page