Figure 10
From: Successful adjuvant-free vaccination of BALB/c mice with mutated amyloid β peptides
Cross reaction of antisera from BALB/c mice vaccinated with different adjuvant-free peptide vaccines to cortex brain section of a 14-month-old APP/PS1 transgenic mouse. Each panel is described below: a. Immunostaining with 6E10 antibody (Signet; Philadelphia, PA). b. Immunostaining with antisera from BALB/c mice vaccinated with PFM peptide. c. Immunostaining with antisera from BALB/c mice vaccinated with P22W peptide. d. Immunostaining with antisera from BALB/c mice vaccinated with P24M peptide. e. Immunostaining with antisera from BALB/c mice vaccinated with PFDM peptide. f. Immunostaining with antisera from BALB/c mice vaccinated with PDM peptide. g. Immunostaining with antisera from BALB/c mice vaccinated with PWT peptide