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Figure 8 | BMC Neuroscience

Figure 8

From: Dimerization of the transmembrane domain of amyloid precursor proteins and familial Alzheimer's disease mutants

Figure 8

APP-TM peptides are not toxic to HEK293 cells stably overexpressing APP and γ-secretase components. HEK293 cells stably expressing Swedish mutant APP and the γ-secretase components were incubated overnight with APP-TM peptides. The SRB cytotoxicity assay was used to determine whether wild-type (black bars) and V717G (clear bars) affected cell survival. Note that neither peptide caused a reduction in cell survival.

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BMC Neuroscience

ISSN: 1471-2202

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