Skip to main content
Figure 6 | BMC Neuroscience

Figure 6

From: Dimerization of the transmembrane domain of amyloid precursor proteins and familial Alzheimer's disease mutants

Figure 6

Comparison to the clinical pathology of AD patients. The dimerization constants of the APP-TM peptides were compared to the A) Aβ42/Aβ40 ratio and B) mean age of onset. The mean age of onset was obtained from all available families [2]. The dissociation constants are positively correlated to the Aβ42/Aβ40 ratios and similarly association constants are equally correlated to the mean age of onset.

Back to article page