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Figure 7 | BMC Neuroscience

Figure 7

From: Potential identity of multi-potential cancer stem-like subpopulation after radiation of cultured brain glioma

Figure 7

In vivo tumorigeneisis of radio-resistant cells derived from human glioblastoma cells by transplanted subpopulation in SCID mouse. Mice were transplanted with radio-resistant A172 cells (A-C) or GBM2 cells (D-F) into the right striatum via stereotaxic injection, and sacrificed at 4 weeks post-transplantation. Frozen sections of brain tumors were stained with hematoxylin and eosin. (A and F) Peculiar tumor mass-like structure (arrow) and blood vascular formation derived from radio-resistant A172 cells (A, × 40 magnification; B, × 100 magnification) and radio-resistant GBM2 cells (D, × 40 magnification; E, × 100 magnification). (C and F) Solid tumor formation derived from radio-resistant A172 cells (C, × 100 magnification) and radio-resistant GBM2 cells (F, × 200 magnification). Scale bars, 100 μm.

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