Figure 4
Effects of diverse antidepressants on [3H]inositol phosphate accumulation. Experiments were conducted as outlined in the legend to Figure 2, except that tissue contents of [3H]inositol phosphates were assayed by Dowex anion exchange chromatography as detailed in Methods. Each bar is the mean ± SEM (N = 9). Each antidepressant agent stimulated significant concentration-dependent accumulations of inositol phosphate (ANOVA, p < 0.001 for each drug).