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Figure 8 | BMC Neuroscience

Figure 8

From: Human neural progenitors express functional lysophospholipid receptors that regulate cell growth and morphology

Figure 8

Morphology changes induced by LPA are blocked the p160ROCK inhibitor Y27632. hES-NEP cells were incubated with vehicle, 100 ng/mL Ptx, 2.5 μM AG1478, 10 μM U0126, or 10 μM Y27632 for 18 hours and then treated with 1 μM LPA for 18 hours. Images of cell morphology were captured after treatment with each inhibitor but before addition of LPA (t = 0), after five hours of LPA treatment (t = 5) and after 18 hours of LPA treatment (t = 18). Data images are consistent with three independent experiments.

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