Figure 6
From: TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy
TDP-43 protein and transcript levels in CNS of transgenic SOD1 G93A mice compared with age matched controls (a) Immunoblot analysis of brain and spinal cord extracts from wild-type (WT) and transgenic mice (SOD1G93A) at 4 months of age. Open arrow, putative dimeric hSOD1 species. (b) Phosphatase treatment of representative brain urea extracts. (c) Quantitative RT-PCR analysis of brain regions and spinal cords from mice.