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Table 1 Squalestatin alters the trafficking of MoPrP105-132 in neuroblastoma cells. The percentage of MoPrP105-132 that co-localised with cellular markers as shown in untreated neuroblastoma cells and cells treated for 24 hours with 1 μM squalestatin. Values shown are mean percent of peptide that co-localises with markers as shown, ± SD, which was calculated after counting a minimum of 3 cells.

From: Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide

  % Co-localisation with MoPrP105-132
  Untreated Squalestatin-treated
CTxB 63% ± 8 5% ± 1
Caveolin-1 73% ± 3 9% ± 3
GM130 41% ± 5 7% ± 2
Grp 78 38% ± 4 3% ± 2
TfR 6% ± 3 68% ± 8
LAMP-1 9% ± 2 40% ± 6