TY - JOUR AU - Wilson, Rona AU - Bate, Clive AU - Boshuizen, Ronald AU - Williams, Alun AU - Brewer, James PY - 2007 DA - 2007/11/22 TI - Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide JO - BMC Neuroscience SP - 99 VL - 8 IS - 1 AB - Neurotoxic peptides derived from the protease-resistant core of the prion protein are used to model the pathogenesis of prion diseases. The current study characterised the ingestion, internalization and intracellular trafficking of a neurotoxic peptide containing amino acids 105–132 of the murine prion protein (MoPrP105-132) in neuroblastoma cells and primary cortical neurons. SN - 1471-2202 UR - https://doi.org/10.1186/1471-2202-8-99 DO - 10.1186/1471-2202-8-99 ID - Wilson2007 ER -